Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy (Adv. Mater. 48/2025)
Alleviating Atherosclerosis via Sonocatalytic Therapy A dual enzyme-mimicking and ultrasound-responsive Nb2C-Pt@HA-PEG nanozyme efficiently eliminates ROS in the atherosclerotic microenvironment and performs anti-inflammatory capability under ultrasound irradiation. Nb2C-Pt@HA-PEG-mediated sonocatalytic therapy (SCT) exerts an outstanding anti-atherosclerosis efficacy by regulating intraplaque redox homeostasis, contributing to lesional shrinkage and a more stable plaque phenotype in plaque-bearing mice. More details can be found in the Research Article by Jianhua Hao and co-workers (DOI: 10.1002/adma.202420189).
Authors
- Xiao Yu Tian (ORCID: https://orcid.org/0000-0003-3472-9898)
- Xinyue Lao
- Yifei Zhao (ORCID: https://orcid.org/0000-0001-6104-2608)
- Sin‐Yi Pang (ORCID: https://orcid.org/0000-0003-1023-5316)
- Jianhua Hao (ORCID: https://orcid.org/0000-0002-6186-5169)
- Qianqian Bai (ORCID: https://orcid.org/0000-0002-6698-3324)
- Yuan Liu (ORCID: https://orcid.org/0000-0002-0024-9290)
Institutions
- Hong Kong Polytechnic University (HK)
- Chinese University of Hong Kong (HK)
Publication Details
- Journal
- Advanced Materials
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/adma.71322
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00