Galectin-1 induces macrophage immunometabolic reprogramming, modulates T cell immunity and attenuates atherosclerotic plaque formation

Gal-1 protects against atherosclerosis associated with reprogramming macrophages and tuning T cell immunity through glycan-dependent and -independent pathways.

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Publication Details

Journal
Atherosclerosis
Published
2025-12-04
DOI
https://doi.org/10.1016/j.atherosclerosis.2025.120608
Primary Topic
Galectins and Cancer Biology
Type
article
Field-Weighted Citation Impact
0.00

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article

Galectin-1 induces macrophage immunometabolic reprogramming, modulates T cell immunity and attenuates atherosclerotic plaque formation

Julian Leberzammer, Alexander Bartelt, Wolfgang Enard, Herbert Kaltner et al.
Atherosclerosis
Galectins and Cancer Biology
article

Galectin-1 induces macrophage immunometabolic reprogramming, modulates T cell immunity and attenuates atherosclerotic plaque formation

Julian Leberzammer, Alexander Bartelt, Wolfgang Enard, Herbert Kaltner, Veit Eckardt, LI Ya, Michael Lacy, Rundan Duan, Yvonne Jansen, Yvonne Döring, Xavier Blanchet, Philipp von Hundelshausen, Joel Guerra, Michael Hristov, Jürgen Bernhagen, Dorothee Atzler, Donato Santovito, Anna-Kristin Ludwig, Eva Briem, Rui Su, Anna Jung, Vasiliki Triantafyllidou
article en

Abstract

Gal-1 protects against atherosclerosis associated with reprogramming macrophages and tuning T cell immunity through glycan-dependent and -independent pathways.

AtherosclerosisVol. 413
Goethe University Frankfurt (DE), University of Bern (CH), University Hospital of Bern (CH), Helmholtz Zentrum München (DE), Munich Cluster for Systems Neurology (DE), German Centre for Cardiovascular Research (DE), Ludwig-Maximilians-Universität München (DE)
Deutsches Zentrum für Herz-Kreislaufforschung, Deutsche Forschungsgemeinschaft, China Scholarship Council
Openalex Percentile: Top 57%
Galectins and Cancer Biology
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