Psoriasis and gut microbes: research advances from mechanism to therapy
Dysbiosis of the gut microbiota is a key factor in the pathogenesis of psoriasis. The regulatory mechanisms of the gut-skin axis offer new insights into the multisystemic associations of psoriasis. Gut microbiota-based therapeutic strategies hold promise as important adjuncts to conventional treatments, laying the foundation for developing novel targeted therapies. This approach carries significant clinical implications for improving the prognosis of psoriasis patients.
Authors
- Zhonghua Bian (ORCID: https://orcid.org/0000-0002-8312-840X)
- Keyun Sun
- Limin Geng (ORCID: https://orcid.org/0000-0003-3597-3091)
- Xin Cong (ORCID: https://orcid.org/0000-0001-5387-1414)
- Yingxue Chu (ORCID: https://orcid.org/0009-0004-8516-4115)
- Xinyu Zhang (ORCID: https://orcid.org/0009-0005-3900-3684)
- Yang Su
- Guoli Wang (ORCID: https://orcid.org/0000-0001-9689-582X)
- Jianfei Chen (ORCID: https://orcid.org/0000-0001-6472-9077)
- Xiaojie Chen (ORCID: https://orcid.org/0009-0002-5173-1164)
Institutions
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Yantaishan Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.3389/fmicb.2025.1711288
- Citations
- 1
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Natural Science Foundation of Shandong Province