Cross-frequency coupling patterns during oddball processing in disorders of consciousness: a delta–gamma predominance

Auditory oddball processing preferentially engages delta-gamma, rather than theta-gamma, coupling in both healthy individuals and DOC patients, supporting the view that PAC signatures are task- and paradigm-specific rather than universal markers of consciousness. Within this framework, a non-significant tendency towards frequency slowing and a reduction in PAC variability in UWS emerge as preliminary, hypothesis-generating features that warrant further investigation in larger, longitudinal and multi-paradigm cohorts.

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Publication Details

Journal
Frontiers in Psychology
Published
2025-12-04
DOI
https://doi.org/10.3389/fpsyg.2025.1710742
Primary Topic
Traumatic Brain Injury Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Cross-frequency coupling patterns during oddball processing in disorders of consciousness: a delta–gamma predominance

Binbin Huang, Hongxing Cui, Wei Li, Qian Liu et al.
Frontiers in Psychology
Traumatic Brain Injury Research
article

Cross-frequency coupling patterns during oddball processing in disorders of consciousness: a delta–gamma predominance

Binbin Huang, Hongxing Cui, Wei Li, Qian Liu, Hongwei Li, Qian Zhang, Deqiang Wang
article en

Abstract

Auditory oddball processing preferentially engages delta-gamma, rather than theta-gamma, coupling in both healthy individuals and DOC patients, supporting the view that PAC signatures are task- and paradigm-specific rather than universal markers of consciousness. Within this framework, a non-significant tendency towards frequency slowing and a reduction in PAC variability in UWS emerge as preliminary, hypothesis-generating features that warrant further investigation in larger, longitudinal and multi-paradigm cohorts.

Frontiers in PsychologyVol. 16
Binzhou Medical University (CN), Shandong University of Aeronautics (CN)
Hong Kong Polytechnic University, Natural Science Foundation of Shandong Province, Binzhou Medical University
Openalex Percentile: Top 50%
Traumatic Brain Injury Research
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