Assessing neurocognitive functioning among adults ageing with and without HIV at the Kenyan Coast: measurement issues and correlates

We demonstrated the feasibility of OCSPlus administration by trained lay persons, its acceptability, and preliminary reliability and validity among low-literacy older adults on the Kenyan coast. Mean cognitive scores were mixed across the two groups. Cognitive performance was associated with several biopsychosocial factors spanning behavioural/lifestyle, sociodemographic, psychosocial, medical and treatment factors. Further validation studies and epidemiological research are needed to understand better the utility of OCSPlus and the cognitive function of these adults.

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Publication Details

Journal
Frontiers in Aging Neuroscience
Published
2025-12-04
DOI
https://doi.org/10.3389/fnagi.2025.1702869
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
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article

Assessing neurocognitive functioning among adults ageing with and without HIV at the Kenyan Coast: measurement issues and correlates

Carophine Nasambu, Charles R. Newton, Patrick N. Mwangala, Gaia Scerif et al.
Frontiers in Aging Neuroscience
Dementia and Cognitive Impairment Research
article

Assessing neurocognitive functioning among adults ageing with and without HIV at the Kenyan Coast: measurement issues and correlates

Carophine Nasambu, Charles R. Newton, Patrick N. Mwangala, Gaia Scerif, Ryan G. Wagner, Amina Abubakar, Mihaela Duta
article en

Abstract

We demonstrated the feasibility of OCSPlus administration by trained lay persons, its acceptability, and preliminary reliability and validity among low-literacy older adults on the Kenyan coast. Mean cognitive scores were mixed across the two groups. Cognitive performance was associated with several biopsychosocial factors spanning behavioural/lifestyle, sociodemographic, psychosocial, medical and treatment factors. Further validation studies and epidemiological research are needed to understand better the utility of OCSPlus and the cognitive function of these adults.

Frontiers in Aging NeuroscienceVol. 17
University of the Witwatersrand (ZA), Pwani University (KE), Oxford Research Group (GB), Warneford Hospital (GB), Kenya Medical Research Institute (KE), University of Oxford (GB), Agincourt Health and Socio-Demographic Surveillance System (ZA), Aga Khan University Nairobi (KE), Science Oxford (GB)
Openalex Percentile: Top 55%
Dementia and Cognitive Impairment Research
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Assessing neurocognitive functioning among adults ageing with and without HIV at the Kenyan Coast: measurement issues and correlates — Carophine Nasambu, Charles R. Newton, et al. · Frontiers in Aging Neuroscience (2025) | TGRS Research Map | TGRS