Identification of a ubiquitin-binding domain protein, CD2AP, in predicting the prognosis and treatment of lung adenocarcinoma

Our study identifies <i>CD2AP</i> as a key oncoprotein in LUAD. Our findings suggest that targeting <i>CD2AP</i> represents a promising therapeutic strategy for patients with LUAD. Integrating <i>CD2AP</i> assessment into clinical practice may enhance personalised treatment planning and prognostic evaluation for patients with LUAD.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-12-04
DOI
https://doi.org/10.3389/fimmu.2025.1726531
Primary Topic
Ubiquitin and proteasome pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of a ubiquitin-binding domain protein, CD2AP, in predicting the prognosis and treatment of lung adenocarcinoma

Qinjin Dai, Mingfeng He, Zhixiang Bo, Li Li et al.
Frontiers in Immunology
Ubiquitin and proteasome pathways
article

Identification of a ubiquitin-binding domain protein, CD2AP, in predicting the prognosis and treatment of lung adenocarcinoma

Qinjin Dai, Mingfeng He, Zhixiang Bo, Li Li, Jin Huang, Ying Ye, Jishan Yin
article en

Abstract

Our study identifies <i>CD2AP</i> as a key oncoprotein in LUAD. Our findings suggest that targeting <i>CD2AP</i> represents a promising therapeutic strategy for patients with LUAD. Integrating <i>CD2AP</i> assessment into clinical practice may enhance personalised treatment planning and prognostic evaluation for patients with LUAD.

Frontiers in ImmunologyVol. 16
Dalian Medical University (CN), Second Affiliated Hospital of Chongqing Medical University (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 65%
Ubiquitin and proteasome pathways
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