Xiaoyao Pill alleviates ulcerative colitis by inhibiting ferroptosis of enterocytes via activating Nrf2/Gpx4 signaling pathway

Taken together, this study evaluates that XYP alleviates DSS-induced colitis mice by inhibiting ferroptosis of enterocytes and its protective effects are associated with activating the Nrf2/Gpx4 signaling pathway.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-12-04
DOI
https://doi.org/10.3389/fphar.2025.1702452
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Xiaoyao Pill alleviates ulcerative colitis by inhibiting ferroptosis of enterocytes via activating Nrf2/Gpx4 signaling pathway

Xiaoping Xing, Ruomei Zhang, Xiaoqing Zhang, Zehua Zhou
Frontiers in Pharmacology
Ferroptosis and cancer prognosis
article

Xiaoyao Pill alleviates ulcerative colitis by inhibiting ferroptosis of enterocytes via activating Nrf2/Gpx4 signaling pathway

Xiaoping Xing, Ruomei Zhang, Xiaoqing Zhang, Zehua Zhou
article en

Abstract

Taken together, this study evaluates that XYP alleviates DSS-induced colitis mice by inhibiting ferroptosis of enterocytes and its protective effects are associated with activating the Nrf2/Gpx4 signaling pathway.

Frontiers in PharmacologyVol. 16
Shanghai Jiao Tong University (CN), International Peace Maternity & Child Health Hospital (CN)
Openalex Percentile: Top 43%
Ferroptosis and cancer prognosis
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