Loss of a primary cilia protein ARL13B promotes TGFβ-1 induced EMT of RPE in proliferative vitreoretinopathy via increasing Smad3 expression
This study demonstrated a crucial role of ARL13B on TGFβ1-induced RPE EMT, highlighting the importance of ARL13B in PVR formation.
Authors
- Xiaofeng Lin (ORCID: https://orcid.org/0000-0002-4596-2196)
- Xinqi Ma
- Miner Yuan (ORCID: https://orcid.org/0000-0002-8988-3289)
- Xiaolai Zhou (ORCID: https://orcid.org/0000-0002-4531-4658)
- Kairui Qiu
- Bingsheng Lou (ORCID: https://orcid.org/0000-0002-4343-8649)
- Xiaobing Qian (ORCID: https://orcid.org/0000-0001-9540-7724)
- Keli Mao
- Yujie Li (ORCID: https://orcid.org/0009-0007-3725-8135)
- Yajun Gong
- Jieting Zeng (ORCID: https://orcid.org/0000-0003-1661-2442)
- Wenjun Sui
Institutions
- University of Electronic Science and Technology of China (CN)
- Sun Yat-sen University (CN)
- Shanghai Eye Disease Prevention & Treatment Center (CN)
- Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
- Southern Medical University Shenzhen Hospital (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.3389/fcell.2025.1661658
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00