Relationship between preoperative plasma fibrinogen and prognosis in patients with non-metastatic gastric cancer: a systematic review and meta-analysis

Elevated preoperative fibrinogen levels are significantly associated with worse overall and recurrence-free survival in patients with non-metastatic gastric cancer, indicating its potential utility as a prognostic biomarker. Given the limited data on RFS, further large-scale prospective studies are needed to validate these findings and support its integration into individualized risk stratification models.