Optimal dosing regimen of ondansetron oral soluble pellicles for preventing postoperative nausea and vomiting after primary total joint arthroplasty: a randomized controlled clinical trial
Compared to the 8 + 8 + 8 mg regimen, both the Preop 16 mg and 16 + 8 mg dosing strategies demonstrated superior efficacy. For high-risk patients, the 16 + 8 mg regimen may represent the optimal therapeutic approach.
Authors
- Yinghao Wang (ORCID: https://orcid.org/0000-0002-0045-3531)
- Zongke Zhou (ORCID: https://orcid.org/0000-0002-9037-4756)
- Haoyang Wang (ORCID: https://orcid.org/0000-0003-3801-1226)
- Long Zhao (ORCID: https://orcid.org/0009-0009-0332-0214)
- Shuping Zhong (ORCID: https://orcid.org/0000-0003-1803-0948)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-12-04
- DOI
- https://doi.org/10.3389/fmed.2025.1702879
- Primary Topic
- Nausea and vomiting management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Science and Technology of Sichuan Province