The regulatory role of circGDI2 in hepatocellular carcinoma proliferation and glycolysis with the involvement of m6A modification
FTO-mediated m<sup>6</sup>A modification of circGDI2 promotes HCC proliferation and glycolysis via the IGF2BP2/PKM2 axis, suggesting circGDI2 as a potential therapeutic target for HCC.
Authors
- Hongxiang Xia (ORCID: https://orcid.org/0000-0003-1657-0107)
- Shiyi Chen (ORCID: https://orcid.org/0000-0002-3955-0101)
- Shuwei Chen (ORCID: https://orcid.org/0009-0005-9646-5949)
Institutions
- Chenzhou First People's Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- Non-coding RNA Research
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1016/j.ncrna.2025.11.006
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00