Clinicopathological data and the role of miRNA expression in patients with pheochromocytomas/paragangliomas
MiR-483-5p emerges as a promising biomarker of aggressive PPGL behavior, while other miRNAs reflect distinct biological behaviors. PD-L1 expression in a subset of cases highlights immune checkpoint inhibition as a potential therapeutic strategy. Prospective validation is warranted.
Authors
- Konstantinos Maltezos
- Vasiliki Vasileiou (ORCID: https://orcid.org/0000-0002-3920-4321)
- Αθανάσιος Παπαθεοδώρου (ORCID: https://orcid.org/0000-0003-0119-847X)
- Eva N. Kassi (ORCID: https://orcid.org/0000-0001-7491-2297)
- Gregory Kaltsas (ORCID: https://orcid.org/0000-0002-5876-7883)
- Georgios Kyriakopoulos (ORCID: https://orcid.org/0000-0002-5853-5361)
- Foteini Thanasoula
- Anna G. Angelousi (ORCID: https://orcid.org/0000-0003-0906-3617)
- Maria P. Yavropoulou (ORCID: https://orcid.org/0000-0002-6501-3692)
- Chrysostomos Maltezos
Institutions
- National and Kapodistrian University of Athens (GR)
- Hellenic Air Force (GR)
- Alexandra Hospital (GR)
- Laiko General Hospital of Athens (GR)
- KAT General Hospital of Attica (GR)
- Evangelismos Hospital (GR)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.3389/fendo.2025.1716806
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 0.00