History of large-for-gestational-age birth is independently associated with subsequent gestational diabetes in Chinese multiparous women: a retrospective cohort study
A history of LGA birth is independently associated with s-GDM risk in Chinese multiparous women, particularly among those without prior dysglycemia, aged <35 years, or with normal BMI. The percentile-defined LGA definition demonstrates superior associative relevance compared to absolute macrosomia, supporting its application in precision screening for multiparous pregnancies.
Authors
- Juan Yang (ORCID: https://orcid.org/0000-0002-5328-0822)
- Kaidong Ma
- Shilin Zhong (ORCID: https://orcid.org/0000-0001-7942-8154)
- Yanmei Li
- Yuqing Deng
- Chang Xu (ORCID: https://orcid.org/0000-0003-3323-9918)
- Min Wang (ORCID: https://orcid.org/0000-0002-8898-8222)
- Ao Yang (ORCID: https://orcid.org/0009-0003-5321-7836)
- Yuzhen Liu (ORCID: https://orcid.org/0000-0002-1660-1578)
- Ying Wang (ORCID: https://orcid.org/0009-0008-3662-2692)
Institutions
- Hong Kong University of Science and Technology (HK)
- Peking University Shenzhen Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.3389/fendo.2025.1678319
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Peking University
- Sanming Project of Medicine in Shenzhen
- Shenzhen Science and Technology Innovation Program