<i>Chlamydia trachomatis</i> -specific T Cell Immunity Reflects Widespread Exposure in South African Adolescents and Young Women
Both the magnitude and quality of the systemic CD4+ T cell responses are critical components of protective immunity to C. trachomatis and may limit mucosal immunopathology, informing vaccine strategies in high-risk populations.
Authors
- Micaela Lurie (ORCID: https://orcid.org/0000-0002-6993-0420)
- Hoyam Gamieldien (ORCID: https://orcid.org/0000-0002-8352-9705)
- Rubina Bunjun (ORCID: https://orcid.org/0000-0002-8471-163X)
- Katherine Gill (ORCID: https://orcid.org/0000-0002-1367-4309)
- Shaun Barnabas (ORCID: https://orcid.org/0000-0002-4819-9501)
- Linda‐Gail Bekker (ORCID: https://orcid.org/0000-0002-0755-4386)
- Smritee Dabee (ORCID: https://orcid.org/0000-0002-8373-9593)
- Shameem Z. Jaumdally (ORCID: https://orcid.org/0000-0003-0316-7087)
- Heather B. Jaspan (ORCID: https://orcid.org/0000-0002-0745-6073)
- David A. Lewis (ORCID: https://orcid.org/0000-0002-5534-8392)
- Dumisile V. Maseko (ORCID: https://orcid.org/0000-0002-9707-9485)
- Jo-Ann S. Passmore (ORCID: https://orcid.org/0009-0002-3151-3514)
Institutions
- National Health Laboratory Service (ZA)
- Desmond Tutu HIV Foundation (ZA)
- University of Cape Town (ZA)
- Stellenbosch University (ZA)
- Centre for the AIDS Programme of Research in South Africa (ZA)
- Sydney Sexual Health Centre (AU)
- Seattle Children's Hospital (US)
- Westmead Institute (AU)
- Sydney Local Health District (AU)
- Westmead Institute for Medical Research (AU)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1093/infdis/jiaf595
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00