Postoperative delirium in patients with free flap reconstruction after head and neck tumor surgery: influencing factors for severity and onset time, and a prediction model

POD after head and neck tumor surgery shows marked heterogeneity in severity and onset. Neutrophils and platelets may respectively drive neuroinflammation occurrence and progression, synergizing with blood pressure to regulate POD subtyping. Identified factors enable early multidimensional warning. The prediction model performs well with optimal threshold 0.45-0.55.

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Publication Details

Journal
BMC Oral Health
Published
2025-12-04
DOI
https://doi.org/10.1186/s12903-025-07461-6
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
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article

Postoperative delirium in patients with free flap reconstruction after head and neck tumor surgery: influencing factors for severity and onset time, and a prediction model

Gaili Chen, Ping Gong, Z Liu, Zi‐Li Yu
BMC Oral Health
Intensive Care Unit Cognitive Disorders
article

Postoperative delirium in patients with free flap reconstruction after head and neck tumor surgery: influencing factors for severity and onset time, and a prediction model

Gaili Chen, Ping Gong, Z Liu, Zi‐Li Yu
article en

Abstract

POD after head and neck tumor surgery shows marked heterogeneity in severity and onset. Neutrophils and platelets may respectively drive neuroinflammation occurrence and progression, synergizing with blood pressure to regulate POD subtyping. Identified factors enable early multidimensional warning. The prediction model performs well with optimal threshold 0.45-0.55.

BMC Oral HealthVol. 26(1)
Wuhan University (CN)
Openalex Percentile: Top 54%
Intensive Care Unit Cognitive Disorders
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