Preclinical Evaluation of Synthetic Bone Graft Materials in an Instrumented Sheep Posterolateral Lumbar Spinal Fusion Model
These results show distinct differences in the performance between commercially available bone graft substitutes, highlighting the importance of utilizing clinically relevant animal models with robust, multi-endpoint analyses to evaluate their efficacy. Specifically, BCP<µm achieved superior fusion rates compared with other synthetic bone grafts when used standalone, further demonstrating its enhanced bone-forming ability in vivo.
Authors
- William Robert Walsh (ORCID: https://orcid.org/0000-0002-5023-6148)
- Joost D. de Bruijn (ORCID: https://orcid.org/0000-0003-0367-3633)
- Dan Wills (ORCID: https://orcid.org/0000-0001-5524-5361)
- Matthew H. Pelletier (ORCID: https://orcid.org/0000-0003-1643-6696)
- Nathan W. Kucko (ORCID: https://orcid.org/0000-0002-4904-8238)
- Florence Barrère‐de Groot
- Tian Wang (ORCID: https://orcid.org/0000-0002-6407-1110)
Institutions
- UNSW Sydney (AU)
Publication Details
- Journal
- Clinical Spine Surgery A Spine Publication
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1097/bsd.0000000000001983
- Citations
- 1
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 1.47