Effects of Different Tissue Factor and Phospholipid Concentrations on Thrombin Generation Assay Parameters in Normal and Abnormal Plasma Samples
Changes in TF concentration affected the lag time time-to-peak, and peak height, while alterations in PL concentration primarily affected the peak height in both normal and abnormal plasma samples. These findings are crucial for assay standardisation; Ci-Trol 2 and Ci-Trol 3 may serve as quality control materials.
Authors
- Mino Sakata
- Osamu Maruyama (ORCID: https://orcid.org/0000-0003-2484-5334)
- Osamu Kumano (ORCID: https://orcid.org/0000-0001-6650-0567)
Institutions
- National Institute of Advanced Industrial Science and Technology (JP)
Publication Details
- Journal
- International Journal of Laboratory Hematology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1111/ijlh.70034
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00