The future of osteoarthritis treatment: exploring the potential of exosomes from adipose tissue-derived stem cells
ADSC-exosomes are a promising cell-free therapy for OA, with reduced immune rejection and tumorigenicity compared to ADSC transplantation. Standardizing exosome isolation and production remains a challenge. Further research is needed to confirm long-term safety and efficacy in humans.
Authors
- Chung‐Hwan Chen (ORCID: https://orcid.org/0000-0001-8941-4792)
- Sung‐Yen Lin (ORCID: https://orcid.org/0000-0002-4191-2183)
- Tien‐Ching Lee (ORCID: https://orcid.org/0000-0002-1510-8079)
- Yin‐Chih Fu
- Pen-Ju Huang
Institutions
- Kaohsiung Medical University (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
Publication Details
- Journal
- Bone and Joint Research
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1302/2046-3758.1412.bjr-2025-0117.r1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00