From Symptom to Outcome: Defining Clinically Meaningful Patient‐Reported Appetite Loss in Non‐Small‐Cell Lung Cancer
We developed a population predictive model to characterize the relationship between patient-reported appetite and body weight, identifying clinically meaningful thresholds for appetite loss. This work highlights the importance of managing appetite loss in oncology care and supports its use as a quantitative endpoint in clinical trials and practice.
Authors
- Quefeng Li (ORCID: https://orcid.org/0000-0003-0707-2763)
- Jim H. Hughes (ORCID: https://orcid.org/0000-0002-1862-5805)
- Benyam Muluneh (ORCID: https://orcid.org/0000-0002-2387-6676)
- Lynne I. Wagner (ORCID: https://orcid.org/0000-0001-9685-4796)
- Yuchen Wang (ORCID: https://orcid.org/0000-0002-6710-6710)
- Jiawei Zhou (ORCID: https://orcid.org/0009-0000-3317-0311)
Institutions
- University of North Carolina at Chapel Hill (US)
- Pfizer (United States) (US)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/jcsm.70150
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00