Persisting Symptoms After Concussion and Functional Neurological Disorder: Points of Intersection

Persistent symptoms after concussion (PSaC) and functional neurological disorder (FND) are frequently encountered in clinical practice and are often challenging to manage due to heterogeneous and polysymptomatic presentations, as well as fragmented care pathways. This review outlines key points of intersection between PSaC and FND across pathophysiology, illness beliefs, rehabilitation models, and emerging treatments. We describe when FND should be considered in the differential diagnosis of patients with PSaC, and provide guidance on history-taking, examination, diagnostic communication, and rehabilitation planning that can be applied to both conditions. We also examine the influence of expectations, clinical messaging, and interactions with the healthcare system on recovery. Integrating principles from FND into concussion care may help clinicians more accurately formulate cases and support individualized rehabilitation pathways.

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Publication Details

Journal
Seminars in Neurology
Published
2025-12-03
DOI
https://doi.org/10.1055/a-2752-8940
Primary Topic
Traumatic Brain Injury Research
Type
article
Field-Weighted Citation Impact
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article

Persisting Symptoms After Concussion and Functional Neurological Disorder: Points of Intersection

Michael DeDominicis, Adriano Mollica, Noah D. Silverberg, Matthew J. Burke
Seminars in Neurology
Traumatic Brain Injury Research
article

Persisting Symptoms After Concussion and Functional Neurological Disorder: Points of Intersection

Michael DeDominicis, Adriano Mollica, Noah D. Silverberg, Matthew J. Burke
article en

Abstract

Persistent symptoms after concussion (PSaC) and functional neurological disorder (FND) are frequently encountered in clinical practice and are often challenging to manage due to heterogeneous and polysymptomatic presentations, as well as fragmented care pathways. This review outlines key points of intersection between PSaC and FND across pathophysiology, illness beliefs, rehabilitation models, and emerging treatments. We describe when FND should be considered in the differential diagnosis of patients with PSaC, and provide guidance on history-taking, examination, diagnostic communication, and rehabilitation planning that can be applied to both conditions. We also examine the influence of expectations, clinical messaging, and interactions with the healthcare system on recovery. Integrating principles from FND into concussion care may help clinicians more accurately formulate cases and support individualized rehabilitation pathways.

Seminars in Neurology
Sunnybrook Health Science Centre (CA), Vancouver Coastal Health (CA), University of British Columbia (CA), Vancouver Coastal Health Research Institute (CA), Sunnybrook Research Institute, Hamilton Health Sciences (CA), McMaster University (CA)
Openalex Percentile: Top 50%
Traumatic Brain Injury Research
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Persisting Symptoms After Concussion and Functional Neurological Disorder: Points of Intersection — Michael DeDominicis, Adriano Mollica, et al. · Seminars in Neurology (2025) | TGRS Research Map | TGRS