Noninferiority of One HPV Vaccine Dose to Two Doses
One dose of either a bivalent or nonavalent HPV vaccine provided protection against HPV16 or HPV18 infection and was not inferior to two doses. (Funded by the National Cancer Institute and others; ESCUDDO ClinicalTrials.gov number, NCT03180034.).
Authors
- Loretto J Carvajal (ORCID: https://orcid.org/0000-0002-4965-7615)
- Byron Romero
- Jean Cyr
- Danping Liu (ORCID: https://orcid.org/0000-0001-5483-6303)
- Aimée R. Kreimer (ORCID: https://orcid.org/0000-0002-6073-2591)
- Mónica S. Sierra
- Karla Coronado
- Daniela Mora
- Rolando Herrero (ORCID: https://orcid.org/0000-0001-5448-3456)
- Carlos Ávila (ORCID: https://orcid.org/0009-0007-2145-7295)
- Gloriana Barrientos
- Joshua N. Sampson (ORCID: https://orcid.org/0000-0003-2875-3365)
- Dora Ruggieri
- Allan Hildesheim (ORCID: https://orcid.org/0000-0003-0257-2363)
- Lígia A. Pinto (ORCID: https://orcid.org/0000-0002-3130-9882)
- Yenory Estrada
- Casey Dagnall (ORCID: https://orcid.org/0000-0001-7334-4718)
- Troy J. Kemp (ORCID: https://orcid.org/0000-0002-1197-7525)
- John Schussler (ORCID: https://orcid.org/0000-0002-8793-0766)
- Mitchell H. Gail (ORCID: https://orcid.org/0000-0002-3919-3263)
- Rebeca Ocampo (ORCID: https://orcid.org/0000-0002-8069-5142)
- John T. Schiller (ORCID: https://orcid.org/0000-0001-7308-950X)
- Michael Zúñiga (ORCID: https://orcid.org/0000-0002-8479-4965)
- Douglas R. Lowy (ORCID: https://orcid.org/0000-0003-0635-219X)
- Stephen J. Chanock (ORCID: https://orcid.org/0000-0002-2324-3393)
- Carolina Porras (ORCID: https://orcid.org/0000-0002-4592-3883)
- Bernal Cortés
- Celia E. Coto
Institutions
- Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud (CR)
- Information Management Services (US)
- Frederick National Laboratory for Cancer Research (US)
- National Cancer Institute (US)
- Center for Cancer Research (US)
- Centre international de recherche sur le cancer (FR)
- Division of Cancer Epidemiology and Genetics
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1056/nejmoa2506765
- Citations
- 18
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 24.38