A combined study of network-based prediction and in vitro experimental validation on the procarcinogenic mechanism of propylparaben in estrogen receptor-positive breast cancer cells
Propylparaben may promote the occurrence and progression of estrogen receptor-positive breast cancer by upregulating SLC2A1 and KIF11, activating metabolic and proliferative pathways, and simultaneously suppressing tumor-suppressive signals.
Authors
- Jiaying Wen (ORCID: https://orcid.org/0000-0002-6566-0099)
- Yanqiu Qin
- Weiliang Sun
- Huijun Zhu
- Yingying Liang
- Haiying Yue
- Laiming Mo
Institutions
- Sun Yat-sen University (CN)
- Guangxi Medical University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1016/j.ecoenv.2025.119504
- Citations
- 1
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 1.82