Haemophilus influenzae dominance in fungal ball microbiome revealed through multi-niche metagenomic sequencing
This study highlights H. influenzae as a critical bacterial biomarker in MSFB. The inverse relationship between H. influenzae and A. flavus may suggest competitive or immune-mediated interactions. These findings advance understanding of non-invasive fungal sinusitis. Future validation in larger fungal ball cohorts or invasive fungal sinusitis is warranted.
Authors
- Chengyao Liu (ORCID: https://orcid.org/0000-0002-0056-9032)
- Yun Zeng (ORCID: https://orcid.org/0000-0002-5747-3349)
- Hongzheng Wei (ORCID: https://orcid.org/0000-0001-6560-572X)
- Yi Wang (ORCID: https://orcid.org/0000-0002-2031-087X)
- Yuan Zhang (ORCID: https://orcid.org/0000-0003-1080-4267)
- Ting Yang (ORCID: https://orcid.org/0000-0002-7097-9213)
- Yunchuan Li (ORCID: https://orcid.org/0000-0002-5099-7764)
- Jie Zhou (ORCID: https://orcid.org/0009-0003-8301-9144)
- Pengyu Shi
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Beijing Institute of Neurosurgery (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1186/s12866-025-04546-8
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00