Clinical performance of triage strategies for HPV-positive women in cervical cancer screening in rural Yunnan China
PAX1 methylation triage demonstrated better clinical performance and required fewer colposcopy referrals than cytology triage. It showed good potential as an triage strategy for HPV-positive women in rural Yunnan. The addition of SOX1 methylation or integration with HPV genotyping did not significantly enhance its clinical performance.
Authors
- Xiuwei Zhai
- Tong Kong
- Dao Yan
- Hongping Zhang (ORCID: https://orcid.org/0000-0002-0076-0419)
- Hongying Yang (ORCID: https://orcid.org/0000-0002-5161-7444)
- Jing Yu (ORCID: https://orcid.org/0009-0009-3028-9312)
- Xue Yang (ORCID: https://orcid.org/0000-0003-2768-1865)
- Rufei Duan (ORCID: https://orcid.org/0000-0001-5669-0176)
Institutions
- Kunming Medical University (CN)
- Yunnan Maternal and Child Health (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1186/s12885-025-15375-3
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00