Relationship between changes in uric acid levels and renal function during 12 months of treatment with luseogliflozin
Changes in eGFR after luseogliflozin administration were significantly correlated with baseline eGFR, uACR, and changes in uric acid levels (Δ uric acid). The change in uric acid levels following SGLT2 inhibitor treatment was associated with metabolic parameters such as blood pressure and albuminuria, suggesting that it may function as a surrogate marker reflecting renal metabolic processes.
Authors
- Ito H (ORCID: https://orcid.org/0000-0002-8143-0082)
- T. Hashimoto (ORCID: https://orcid.org/0000-0001-6178-7204)
- Suzuko Matsumoto
- Takuma Izutsu (ORCID: https://orcid.org/0009-0006-4747-0327)
- Shinichi Antoku
- Takashi Sugawara (ORCID: https://orcid.org/0000-0003-4621-8710)
- Hideyuki Inoue
- Toshiko Mori
- Hashimoto Yo
- Sugitatsu Yoshito
Institutions
- Iwate Prefectural Central Hospital (JP)
- Edogawa Hospital (JP)
Publication Details
- Journal
- Diabetology International
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1007/s13340-025-00853-7
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00