Focal Atrial Tachycardia During Central Gemcitabine Administration

Gemcitabine has the capability to be directly arrhythmogenic. Centrally placed lines can abut the endocardium or vascular endothelial surface, which may counteract the intention to dilute therapeutic agents in large volumes of blood. A clear temporal relationship between symptom and medication should prompt consideration of the therapeutic as the causative agent.

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Publication Details

Journal
JACC Case Reports
Published
2025-12-03
DOI
https://doi.org/10.1016/j.jaccas.2025.106302
Citations
1
Primary Topic
Chemotherapy-induced cardiotoxicity and mitigation
Type
article
Field-Weighted Citation Impact
1.39
Controls
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article

Focal Atrial Tachycardia During Central Gemcitabine Administration

Shaumik Adhya, Jaspal Singh Gill, A. S. Sethi, Andrew D’Silva et al.
1 citations
JACC Case Reports
Chemotherapy-induced cardiotoxicity and mitigation
1.39
article

Focal Atrial Tachycardia During Central Gemcitabine Administration

Shaumik Adhya, Jaspal Singh Gill, A. S. Sethi, Andrew D’Silva, Marco Pinto, John Whitaker
article en
1 citations

Abstract

Gemcitabine has the capability to be directly arrhythmogenic. Centrally placed lines can abut the endocardium or vascular endothelial surface, which may counteract the intention to dilute therapeutic agents in large volumes of blood. A clear temporal relationship between symptom and medication should prompt consideration of the therapeutic as the causative agent.

JACC Case ReportsVol. 31(3)
Guy's and St Thomas' NHS Foundation Trust (GB)
Openalex Percentile: Top 13%
Chemotherapy-induced cardiotoxicity and mitigation
1.39
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