Condensation of fluconazole and zinc undecylanate particles using low-pressure RF plasma: a novel drug combination approach

This study successfully demonstrated, for the first time, the plasma-assisted condensation of FCZ with ZU into a single antifungal preparation. The novel compound has the potential to shorten treatment duration, prevent relapse, and overcome resistance in persistent and recurrent mycosis infections. The findings highlight LPRFP as a promising method for combining multiple pharmacotherapeutic agents into innovative formulations with enhanced clinical potential.

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Publication Details

Journal
BMC Pharmacology and Toxicology
Published
2025-12-03
DOI
https://doi.org/10.1186/s40360-025-01048-1
Primary Topic
Plasma Applications and Diagnostics
Type
article
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article

Condensation of fluconazole and zinc undecylanate particles using low-pressure RF plasma: a novel drug combination approach

Ferhat Bozduman, Namık Bilici
BMC Pharmacology and Toxicology
Plasma Applications and Diagnostics
article

Condensation of fluconazole and zinc undecylanate particles using low-pressure RF plasma: a novel drug combination approach

Ferhat Bozduman, Namık Bilici
article en

Abstract

This study successfully demonstrated, for the first time, the plasma-assisted condensation of FCZ with ZU into a single antifungal preparation. The novel compound has the potential to shorten treatment duration, prevent relapse, and overcome resistance in persistent and recurrent mycosis infections. The findings highlight LPRFP as a promising method for combining multiple pharmacotherapeutic agents into innovative formulations with enhanced clinical potential.

BMC Pharmacology and ToxicologyVol. 27(1)
Karabük University (TR)
Openalex Percentile: Top 47%
Plasma Applications and Diagnostics
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