Condensation of fluconazole and zinc undecylanate particles using low-pressure RF plasma: a novel drug combination approach
This study successfully demonstrated, for the first time, the plasma-assisted condensation of FCZ with ZU into a single antifungal preparation. The novel compound has the potential to shorten treatment duration, prevent relapse, and overcome resistance in persistent and recurrent mycosis infections. The findings highlight LPRFP as a promising method for combining multiple pharmacotherapeutic agents into innovative formulations with enhanced clinical potential.
Authors
- Ferhat Bozduman (ORCID: https://orcid.org/0000-0002-2669-021X)
- Namık Bilici (ORCID: https://orcid.org/0000-0002-4320-3567)
Institutions
- Karabük University (TR)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1186/s40360-025-01048-1
- Primary Topic
- Plasma Applications and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00