Defining the Standard of Care in Fournier’s Gangrene—An Umbrella Review

We conducted an umbrella review, a review including only systematic reviews and meta-analyses, about the standard of care for Fournier's gangrene (FG), which is a life-threatening and rare bacterial infection, and the clinical outcomes have not improved in recent years. In summary, FG is consistently described as a multimodal emergency, centered on three core interventions: early surgical debridement, empiric broad-spectrum antibiotics, and intensive supportive care; however, despite advances in care, FG is still associated with high mortality and morbidity. Consequently, further robust research is needed.