Challenging laparoscopic radical nephrectomy in pregnancy

Renal cell carcinoma (RCC) during pregnancy is rare and presents a unique clinical dilemma, requiring the simultaneous optimisation of maternal oncological outcomes and fetal safety. Management decisions must balance the urgency of treating a potentially aggressive malignancy against the physiological and obstetric risks of intervention. We present the case of a large, incidentally detected clear cell RCC in a pregnant patient, managed successfully with laparoscopic radical nephrectomy during the second trimester. This case underscores the importance of multidisciplinary collaboration and tailored surgical planning in achieving favourable outcomes for both the mother and fetus.

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Publication Details

Journal
BMJ Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1136/bcr-2025-269646
Primary Topic
Cancer Risks and Factors
Type
article
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article

Challenging laparoscopic radical nephrectomy in pregnancy

Ahmad Alam, Avi Raman, Matthew Kwon, Esmat Mansour
BMJ Case Reports
Cancer Risks and Factors
article

Challenging laparoscopic radical nephrectomy in pregnancy

Ahmad Alam, Avi Raman, Matthew Kwon, Esmat Mansour
article en

Abstract

Renal cell carcinoma (RCC) during pregnancy is rare and presents a unique clinical dilemma, requiring the simultaneous optimisation of maternal oncological outcomes and fetal safety. Management decisions must balance the urgency of treating a potentially aggressive malignancy against the physiological and obstetric risks of intervention. We present the case of a large, incidentally detected clear cell RCC in a pregnant patient, managed successfully with laparoscopic radical nephrectomy during the second trimester. This case underscores the importance of multidisciplinary collaboration and tailored surgical planning in achieving favourable outcomes for both the mother and fetus.

BMJ Case ReportsVol. 18(12)
Hunter New England Local Health District (AU)
Openalex Percentile: Top 47%
Cancer Risks and Factors
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