Matrix Stiffness Directs Early Injury and Ketogenesis Programs to Prime Kidney Repair
Mfap2, a fibroblast/pericyte-derived core matrisome component, preserved kidney architecture and supported tubular ketogenesis by regulating Hmgcs2 via Esr2 in the AKI microenvironment.
Authors
- Cameron Jones (ORCID: https://orcid.org/0000-0002-7269-1045)
- Wenxue Li (ORCID: https://orcid.org/0000-0002-8902-0184)
- H. Bradley Shaffer (ORCID: https://orcid.org/0000-0002-5795-9242)
- Yansheng Liu (ORCID: https://orcid.org/0000-0002-2626-3912)
- Silvia Liu (ORCID: https://orcid.org/0000-0002-1840-9520)
- Dong Zhou (ORCID: https://orcid.org/0000-0003-1981-8745)
- Yuan Gui (ORCID: https://orcid.org/0000-0001-7053-580X)
- Yanbao Yu (ORCID: https://orcid.org/0000-0003-2994-1974)
- Jianzhong Li (ORCID: https://orcid.org/0000-0001-8100-975X)
- Yuanyuan Wang (ORCID: https://orcid.org/0000-0002-6693-643X)
- Kelly Zheng (ORCID: https://orcid.org/0009-0002-3288-371X)
- Jiajun Liu (ORCID: https://orcid.org/0000-0002-5301-8314)
- Samantha Mae Mallari
Institutions
- University of Connecticut (US)
- University of Pittsburgh (US)
- Yale Cancer Center (US)
- Yale University (US)
- University of Delaware (US)
Publication Details
- Journal
- Journal of the American Society of Nephrology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1681/asn.0000000967
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.00