Determining the Use and Reasons for Non-De-Escalation of Empiric Carbapenem Therapy in a Private Hospital in South Africa

The study came to the conclusion that prescribers do not want to de-escalate once their patients are improving on current treatment or if there are no cultures available.

Authors

Lindi Angeline Mabope (ORCID: https://orcid.org/0000-0002-5155-7381)
Phumzile Skosana (ORCID: https://orcid.org/0000-0002-2873-2735)
Petro de Klerk

Institutions

Sefako Makgatho Health Sciences University (ZA)

Publication Details

Journal: Antibiotics
Published: 2025-12-03
DOI: https://doi.org/10.3390/antibiotics14121220
Primary Topic: Antibiotic Use and Resistance
Type: article
Field-Weighted Citation Impact: 0.00

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article

Determining the Use and Reasons for Non-De-Escalation of Empiric Carbapenem Therapy in a Private Hospital in South Africa

Lindi Angeline Mabope, Phumzile Skosana, Petro de Klerk

Dec 3, 2025

Antibiotics

Antibiotic Use and Resistance

article

Determining the Use and Reasons for Non-De-Escalation of Empiric Carbapenem Therapy in a Private Hospital in South Africa

Lindi Angeline Mabope, Phumzile Skosana, Petro de Klerk

December 3, 2025article en

Abstract

The study came to the conclusion that prescribers do not want to de-escalate once their patients are improving on current treatment or if there are no cultures available.

AntibioticsVol. 14(12)

Sefako Makgatho Health Sciences University (ZA)

Openalex Percentile: Top 55%

Antibiotic Use and Resistance

DOI Open Access PDF OpenAlex

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Determining the Use and Reasons for Non-De-Escalation of Empiric Carbapenem Therapy in a Private Hospital in South Africa — Lindi Angeline Mabope, Phumzile Skosana, et al. · Antibiotics (2025) | TGRS Research Map | TGRS