Treatment responses and relapse predictors in pediatric CNO: insights from a referral center
Conventional DMARDs are effective in a limited subset of CNO patients, who may represent a milder disease phenotype. The presence of skin involvement and a greater number of affected bones may both suggest a more aggressive disease course. Anti-TNF therapies are the most effective agents, while other biologics offer promising results in resistant cases. Prospective studies are needed to guide individualized treatment strategies.
Authors
- Mehmet Orhan Erkan (ORCID: https://orcid.org/0000-0002-1639-5196)
- Yelda Bilginer (ORCID: https://orcid.org/0000-0002-6232-0072)
- Hazel Delal Dara Kar
- Veysel Çam (ORCID: https://orcid.org/0000-0001-6629-3967)
- Hülya Ercan Emreol (ORCID: https://orcid.org/0000-0003-0138-8791)
- Ozlem Necipoglu (ORCID: https://orcid.org/0000-0002-6426-2857)
- E. Cingoz
- Özge Başaran
- Yağmur Bayındır (ORCID: https://orcid.org/0000-0001-5274-3285)
- Erdal Sağ (ORCID: https://orcid.org/0000-0002-6542-2656)
- Dilara Ünal (ORCID: https://orcid.org/0000-0002-3043-792X)
- Seza Özen (ORCID: https://orcid.org/0000-0002-2389-7282)
Institutions
- Hacettepe University (TR)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1093/rheumatology/keaf645
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00