Influence of ventilatory settings on pendelluft and expiratory muscle activity in hypoxemic patients resuming spontaneous breathing
In patients with ARDS transitioning to spontaneous breathing, increasing PS reduces pendelluft and expiratory muscle activity. Higher PEEP can decrease pendelluft, but its effect can be counteracted by increased expiratory activity.
Authors
- Juan N. Medel
- Carol Flores-Rivera (ORCID: https://orcid.org/0000-0001-8888-6819)
- Daniel H. Arellano (ORCID: https://orcid.org/0000-0003-3743-2053)
- Jan Bakker (ORCID: https://orcid.org/0000-0003-2236-7391)
- Alejandro Bruhn (ORCID: https://orcid.org/0000-0001-8034-1937)
- Marisol Bravo
- Nivia R. Estuardo
- Layse Siqueira Costa Miranda (ORCID: https://orcid.org/0000-0001-5942-4666)
- Rodrigo Cornejo (ORCID: https://orcid.org/0000-0002-0497-5740)
- Eduardo Paredes
- Laurent Brochard (ORCID: https://orcid.org/0000-0002-7456-906X)
- Maria J. Martín (ORCID: https://orcid.org/0000-0003-2917-5691)
- Marcelo B. P. Amato (ORCID: https://orcid.org/0000-0003-3525-8282)
- Caio C. A. Morais (ORCID: https://orcid.org/0000-0002-8006-9475)
- Alejandro Donoso Fuentes (ORCID: https://orcid.org/0000-0003-0264-8049)
- Verónica Rojas (ORCID: https://orcid.org/0009-0007-1478-7085)
- Marioli T. Lazo
- Roberto Brito
Institutions
- St. Michael's Hospital (CA)
- Pontificia Universidad Católica de Chile (CL)
- University of Toronto (CA)
- Erasmus MC (NL)
- Universidad Andrés Bello (CL)
- Hospital Clínico de la Universidad de Chile (CL)
- Hospital das Clínicas da Universidade Federal de Pernambuco (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- University of Chile (CL)
Publication Details
- Journal
- Critical Care
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1186/s13054-025-05784-y
- Citations
- 2
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.04