Clinical features and microbiological analysis of risk factors for mortality among patients with carbapenem-resistant Klebsiella pneumoniae bacteremia: A changing virulence landscape
Virulence plasmids generally heighten CRKP strain virulence and directly affect the 7-day survival rate. Certain strains carry virulence plasmids without increased virulence. Community-acquired infection, neurology department admission, and stroke are independent risk factors for pV-CRKP strains. The presence of IncFrepB among pV-CRKP may promote the spread of virulence genes in ST11-type CRKP.
Authors
- Linping Fan
- Dandan Wei (ORCID: https://orcid.org/0000-0002-5597-6233)
- Peng Liu
- Binghui Huo (ORCID: https://orcid.org/0009-0009-1869-3558)
- Yang Liu (ORCID: https://orcid.org/0000-0001-5553-3646)
- Yuxuan Liu (ORCID: https://orcid.org/0000-0003-4426-9290)
- S.D. Huang (ORCID: https://orcid.org/0000-0001-8046-3985)
- QiSen Huanga
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Journal of Microbiology Immunology and Infection
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.jmii.2025.12.001
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00