Multichannel intraluminal impedance-pH monitoring for evaluation of gastroesophageal reflux mimics in infants with comorbidities

Despite higher prevalence of extra-esophageal presentations among all infants with comorbidities, abnormal rates of 24-h esophageal MII-pH monitoring were significantly lower compared with those of infants with esophageal presentations. Routine use of proton-pump inhibitor is not warranted for non-esophageal symptoms in high-risk infants with undocumented gastroesophageal reflux disease.

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Publication Details

Journal
Pediatrics & Neonatology
Published
2025-12-01
DOI
https://doi.org/10.1016/j.pedneo.2025.06.011
Primary Topic
Gastroesophageal reflux and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Multichannel intraluminal impedance-pH monitoring for evaluation of gastroesophageal reflux mimics in infants with comorbidities

En-Shuo Chang, Hsun‐Chin Chao, Pai‐Jui Yeh, Ming‐Wei Lai et al.
Pediatrics & Neonatology
Gastroesophageal reflux and treatments
article

Multichannel intraluminal impedance-pH monitoring for evaluation of gastroesophageal reflux mimics in infants with comorbidities

En-Shuo Chang, Hsun‐Chin Chao, Pai‐Jui Yeh, Ming‐Wei Lai, Mi-Chi Chen, Chih‐Yung Chiu, Chih‐Cheng Chen
article en

Abstract

Despite higher prevalence of extra-esophageal presentations among all infants with comorbidities, abnormal rates of 24-h esophageal MII-pH monitoring were significantly lower compared with those of infants with esophageal presentations. Routine use of proton-pump inhibitor is not warranted for non-esophageal symptoms in high-risk infants with undocumented gastroesophageal reflux disease.

Pediatrics & Neonatology
Chang Gung University (TW), Chang Gung Memorial Hospital (TW), Taoyuan Chang Gung Memorial Hospital (TW), Linkou Chang Gung Memorial Hospital (TW)
Openalex Percentile: Top 46%
Gastroesophageal reflux and treatments
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Multichannel intraluminal impedance-pH monitoring for evaluation of gastroesophageal reflux mimics in infants with comorbidities — En-Shuo Chang, Hsun‐Chin Chao, et al. · Pediatrics & Neonatology (2025) | TGRS Research Map | TGRS