Multi-omics highlights the impacts of cryptorchidism history on immune microenvironment variation in TGCT
We revealed unique molecular pathways in TGCT samples with cryptorchidism history and identified tumor-related features in cryptorchidism accumulation. Cryptorchidism history significantly remodels the immune microenvironment of TGCT.
Authors
- Chenyang Wei (ORCID: https://orcid.org/0000-0002-2327-9273)
- Hailang Fan
- Dake Zhang (ORCID: https://orcid.org/0000-0001-9508-8209)
- Li Gao (ORCID: https://orcid.org/0000-0003-2927-1827)
- Yina Ma (ORCID: https://orcid.org/0000-0002-5457-0354)
- Mengtong Wang
- Yuanhao Chen (ORCID: https://orcid.org/0009-0002-0793-0940)
- Steven J. Schrodi (ORCID: https://orcid.org/0000-0003-2304-8528)
- Xin Zhang (ORCID: https://orcid.org/0000-0003-2138-5600)
- Yaqian Zhao
- Haikun Zhang (ORCID: https://orcid.org/0000-0003-4586-3339)
- Lanlan Sun (ORCID: https://orcid.org/0000-0002-3290-6101)
- Yu Zhao
- Feifan Zhang (ORCID: https://orcid.org/0009-0008-4850-7472)
Institutions
- University of Wisconsin–Madison (US)
- Nanyang Technological University (SG)
- Capital Medical University (CN)
- Beihang University (CN)
- University of California, Davis (US)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1007/s12672-025-04176-6
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00