Malignancy Ratio in Pediatric Patients with Hereditary Multiple Exostoses: True Association or Reporting Bias?

Although a definitive causal relationship cannot be established, hematologic malignancies in pediatric HME patients appear to be disproportionately represented among reported cases. This finding highlights the need for further investigation through large-scale, population-based studies incorporating both clinical and genetic data.

Authors

E. Esposito (ORCID: https://orcid.org/0009-0001-0633-6141)
Salvatore Savasta (ORCID: https://orcid.org/0000-0001-9238-0749)
Francesco Fabrizio Comisi (ORCID: https://orcid.org/0009-0002-8525-3041)
Andrea Maria Comisi (ORCID: https://orcid.org/0009-0004-5479-4333)

Institutions

University of Catania (IT)
Ospedale Microcitemico (IT)

Publication Details

Journal: Pediatric Reports
Published: 2025-12-03
DOI: https://doi.org/10.3390/pediatric17060132
Primary Topic: Bone Tumor Diagnosis and Treatments
Type: article
Field-Weighted Citation Impact: 0.00

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

Malignancy Ratio in Pediatric Patients with Hereditary Multiple Exostoses: True Association or Reporting Bias?

E. Esposito, Salvatore Savasta, Francesco Fabrizio Comisi, Andrea Maria Comisi

Dec 3, 2025

Pediatric Reports

Bone Tumor Diagnosis and Treatments

article

Malignancy Ratio in Pediatric Patients with Hereditary Multiple Exostoses: True Association or Reporting Bias?

E. Esposito, Salvatore Savasta, Francesco Fabrizio Comisi, Andrea Maria Comisi

December 3, 2025article en

Abstract

Although a definitive causal relationship cannot be established, hematologic malignancies in pediatric HME patients appear to be disproportionately represented among reported cases. This finding highlights the need for further investigation through large-scale, population-based studies incorporating both clinical and genetic data.

Pediatric ReportsVol. 17(6)

University of Catania (IT), Ospedale Microcitemico (IT)

Openalex Percentile: Top 46%

Bone Tumor Diagnosis and Treatments

DOI Open Access PDF OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Malignancy Ratio in Pediatric Patients with Hereditary Multiple Exostoses: True Association or Reporting Bias? — E. Esposito, Salvatore Savasta, et al. · Pediatric Reports (2025) | TGRS Research Map | TGRS