Evaluation of GPA, molGPA and prognostic factors in melanoma brain metastases: a single-center study

Both GPA and molGPA were validated as significant predictors of OS in patients with melanoma-associated BM. However, GPA emerged as the sole score significantly associated with both OS and IPFS, suggesting a potential advantage in its clinical utility. The validation of GPA and molGPA as significant predictors for OS in a real clinical setting support their use in guiding treatment recommendations.

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Publication Details

Journal
Clinical & Translational Oncology
Published
2025-12-03
DOI
https://doi.org/10.1007/s12094-025-04118-2
Primary Topic
Melanoma and MAPK Pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of GPA, molGPA and prognostic factors in melanoma brain metastases: a single-center study

Daniel Medenwald, Dirk Vordermark, Jörg Andreas Müller, Niklas Mittenbacher et al.
Clinical & Translational Oncology
Melanoma and MAPK Pathways
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Evaluation of GPA, molGPA and prognostic factors in melanoma brain metastases: a single-center study

Daniel Medenwald, Dirk Vordermark, Jörg Andreas Müller, Niklas Mittenbacher, Jens Christian Philippi
article en

Abstract

Both GPA and molGPA were validated as significant predictors of OS in patients with melanoma-associated BM. However, GPA emerged as the sole score significantly associated with both OS and IPFS, suggesting a potential advantage in its clinical utility. The validation of GPA and molGPA as significant predictors for OS in a real clinical setting support their use in guiding treatment recommendations.

Clinical & Translational Oncology
University Hospital Magdeburg (DE), University Hospital in Halle (DE)
Openalex Percentile: Top 66%
Melanoma and MAPK Pathways
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