Aberrant expression of miR1271-5p in polycystic ovary syndrome and its regulatory effect on granulosa cells via targeting PRKAR1A
miR-1271-5p served as a biomarker for PCOS, predicting disease risk and diagnosing disease onset. The miR-1271-5p/PRKAR1A axis regulated granulosa cell injury under LPS, which can be considered a potential therapeutic target for PCOS.
Authors
- Yanxia Huang (ORCID: https://orcid.org/0000-0002-5690-9649)
- Yanni Lv (ORCID: https://orcid.org/0000-0002-7976-2643)
- Xuehua Cai
- Kexin Chen (ORCID: https://orcid.org/0000-0003-4248-7681)
- Aizhen Pan
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
Publication Details
- Journal
- Endokrynologia Polska
- Published
- 2025-12-03
- DOI
- https://doi.org/10.5603/ep.108079
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00