A minimal electrical model of the human heart

We develop a minimal whole-heart model that describes cardiac electrical conduction and simulate a basic three-lead electrocardiogram (ECG). We compare our three-lead ECG model with clinical data from a Norwegian athlete database. The results demonstrate a strong correlation with the ECGs recorded for these athletes. We simulate various pathologies of the heart's electrical conduction system, including ventricular tachycardia, atrioventricular nodal reentrant tachycardia, accessory pathways, and ischemia-related arrhythmias, showing that the three-lead ECGs align with the clinical data. This minimal model serves as a computationally efficient digital twin of the heart.

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Publication Details

Journal
Chaos An Interdisciplinary Journal of Nonlinear Science
Published
2025-12-01
DOI
https://doi.org/10.1063/5.0292946
Primary Topic
Cardiovascular Effects of Exercise
Type
article
Field-Weighted Citation Impact
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article

A minimal electrical model of the human heart

João Olívia, Rui Dilão
Chaos An Interdisciplinary Journal of Nonlinear Science
Cardiovascular Effects of Exercise
article

A minimal electrical model of the human heart

João Olívia, Rui Dilão
article en

Abstract

We develop a minimal whole-heart model that describes cardiac electrical conduction and simulate a basic three-lead electrocardiogram (ECG). We compare our three-lead ECG model with clinical data from a Norwegian athlete database. The results demonstrate a strong correlation with the ECGs recorded for these athletes. We simulate various pathologies of the heart's electrical conduction system, including ventricular tachycardia, atrioventricular nodal reentrant tachycardia, accessory pathways, and ischemia-related arrhythmias, showing that the three-lead ECGs align with the clinical data. This minimal model serves as a computationally efficient digital twin of the heart.

Chaos An Interdisciplinary Journal of Nonlinear ScienceVol. 35(12)
Institute for Biotechnology and Bioengineering (PT)
Openalex Percentile: Top 45%
Cardiovascular Effects of Exercise
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