The current evidence regarding the efficacy of tezepelumab administered for asthma on T2-related comorbidities

Tezepelumab treatment showed undeniable benefits on CRSwNP and AERD by improving sino-nasal and asthma outcomes. If the efficacy of tezepelumab on severe allergic asthma is well documented, current data are insufficient to conclude on its impact on AR. The effects of tezepelumab on AD and CSU were disappointing. No consistent data exists regarding FA and EE. Future studies are needed to confirm the efficacy of tezepelumab on AR, FA, and EE.

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Publication Details

Journal
Expert Review of Respiratory Medicine
Published
2025-12-03
DOI
https://doi.org/10.1080/17476348.2025.2600110
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
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article

The current evidence regarding the efficacy of tezepelumab administered for asthma on T2-related comorbidities

Angelica I. Tiotiu
Expert Review of Respiratory Medicine
Asthma and respiratory diseases
article

The current evidence regarding the efficacy of tezepelumab administered for asthma on T2-related comorbidities

Angelica I. Tiotiu
article en

Abstract

Tezepelumab treatment showed undeniable benefits on CRSwNP and AERD by improving sino-nasal and asthma outcomes. If the efficacy of tezepelumab on severe allergic asthma is well documented, current data are insufficient to conclude on its impact on AR. The effects of tezepelumab on AD and CSU were disappointing. No consistent data exists regarding FA and EE. Future studies are needed to confirm the efficacy of tezepelumab on AR, FA, and EE.

Expert Review of Respiratory MedicineVol. 20(1)
Cliniques Universitaires Saint-Luc (BE), UCLouvain Saint-Louis Brussels (BE), Hôpital Saint-Luc (CA), UCLouvain (BE)
Openalex Percentile: Top 53%
Asthma and respiratory diseases
DOISourceOpenAlex
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The current evidence regarding the efficacy of tezepelumab administered for asthma on T2-related comorbidities — Angelica I. Tiotiu · Expert Review of Respiratory Medicine (2025) | TGRS Research Map | TGRS