Efficacy of sequential letrozole and gonadotropin therapy for ovulation induction in women with polycystic ovary syndrome: a systematic review and meta-analysis
The treatment group saw a significant rise in ovulation rates and endometrial thickness. Sequential letrozole and gonadotropin therapy (LE + G) may hold clinical significance, but further large-scale, high-quality studies are necessary to establish conclusive evidence.
Authors
- Basir Afzaal Gill
- Muhammad Nabeel Saddique (ORCID: https://orcid.org/0009-0005-9490-5365)
- Mahwish Naseer (ORCID: https://orcid.org/0000-0001-7231-826X)
- Muhammad Usman (ORCID: https://orcid.org/0000-0002-3128-3969)
- Aamir Ijaz (ORCID: https://orcid.org/0000-0002-6764-667X)
- Muhammad Zaman (ORCID: https://orcid.org/0009-0002-6411-7358)
- Malik Saad Hayat (ORCID: https://orcid.org/0009-0000-2462-5724)
- Fatima Shahid
- Waseem Sajjad (ORCID: https://orcid.org/0000-0003-1112-4773)
- Muhammad Atif Bashir
- Ursula Abu Nahla
- Muhammad Safiullah (ORCID: https://orcid.org/0009-0003-7773-2605)
Institutions
- Hebron University (PS)
- King Edward Medical University (PK)
- Baim Institute for Clinical Research (US)
Publication Details
- Journal
- Annals of Medicine and Surgery
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1097/ms9.0000000000004506
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00