The Prognostic Value of Integrating Copy Number Alteration Profiles in NPM1-Mutated Acute Myeloid Leukemia: An Exploratory Study
This exploratory study suggests that combining CNAs and gene mutation profiles may potentially improve the existing prognostic evaluation system for <i>NPM1</i>-mutated AML patients. Confirmation of these results requires additional validation in larger prospective cohorts.
Authors
- Zhenling Li (ORCID: https://orcid.org/0000-0002-6623-1683)
- Chundi Liu
- Dongmei Zhang (ORCID: https://orcid.org/0000-0002-3111-8728)
- Chunxia Zhang (ORCID: https://orcid.org/0000-0001-9639-4507)
- Ming Gong (ORCID: https://orcid.org/0000-0002-1130-5366)
- Li Gao (ORCID: https://orcid.org/0009-0007-7704-3470)
Institutions
- China-Japan Friendship Hospital (CN)
Publication Details
- Journal
- The Application of Clinical Genetics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/tacg.s559124
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China