Central Venous Catheter Selection, Management, and Treatment of Catheter-Associated Deep Vein Thrombosis in Children Undergoing Cardiac Surgery: A Survey of Pediatric Cardiac Critical Care Consortium Centers

<b>Objective:</b> Children undergoing surgery for congenital heart disease (CHD) are at risk for catheter-associated deep vein thrombosis (CA-DVT). We sought to understand the practice variations which may impact the risk for CA-DVT by conducting a comprehensive survey. <b>Methods:</b> Analysis of electronic survey of Pediatric Cardiac Critical Care Consortium (PC<sup>4</sup>) hospitals caring for children undergoing surgery for CHD. <b>Results:</b> Responses from 45 respondent PC4 centers was analyzed; 71% of centers (n = 32) had a prophylactic anticoagulation protocol. Two of the 45 respondent centers utilized a protocol for proactive screening for CA-DVT; 64% of centers (29/45) treated CA-DVT for a duration of 6 to 12 weeks. Internal jugular central vein catheters (CVC) were the most common primary access in children who were 1 to 18 years of age undergoing surgery (89% [40/45] of centers) and in infants 1 to 12 months of age (73% [33/45] of centers). Significant variability CVC-type selection was reported in neonates (<30 days of age). More than half of centers reported avoiding upper extremity peripherally inserted central catheter placement in patients both prior to and after stage 2 palliation for single ventricle CHD (58% [26/45] and 53% [24/45], respectively). <b>Conclusions:</b> Significant variability in prevention and management of CA-DVT is reported among PC<sup>4</sup> centers. Only half of respondent PC4 centers reported having an established treatment protocol for CA-DVT. Consensus and evidence-based guidelines for the treatment of CA-DVT are not consistently followed with only 62% (28/45) of centers reported treating for the recommended 6 to 12 weeks with anticoagulation. There is high variability in CVC-type and location selection in neonates undergoing CHD surgery.

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Journal
World Journal for Pediatric and Congenital Heart Surgery
Published
2025-12-03
DOI
https://doi.org/10.1177/21501351251391768
Primary Topic
Central Venous Catheters and Hemodialysis
Type
article
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article

Central Venous Catheter Selection, Management, and Treatment of Catheter-Associated Deep Vein Thrombosis in Children Undergoing Cardiac Surgery: A Survey of Pediatric Cardiac Critical Care Consortium Centers

David K. Werho, Brian S. Marcus, Jason Patregnani, Ashish A. Ankola et al.
World Journal for Pediatric and Congenital Heart Surgery
Central Venous Catheters and Hemodialysis
article

Central Venous Catheter Selection, Management, and Treatment of Catheter-Associated Deep Vein Thrombosis in Children Undergoing Cardiac Surgery: A Survey of Pediatric Cardiac Critical Care Consortium Centers

David K. Werho, Brian S. Marcus, Jason Patregnani, Ashish A. Ankola, Sirine Baltagi, Laura A. Downey, Wenying Zhang, Kurt R. Schumacher, Therese M. Giglia, Jarrett Linder, John S. Kim, Darren Klugman, Jessica Baylor, Eric L. Bressler, Justin Yeh
article en

Abstract

<b>Objective:</b> Children undergoing surgery for congenital heart disease (CHD) are at risk for catheter-associated deep vein thrombosis (CA-DVT). We sought to understand the practice variations which may impact the risk for CA-DVT by conducting a comprehensive survey. <b>Methods:</b> Analysis of electronic survey of Pediatric Cardiac Critical Care Consortium (PC<sup>4</sup>) hospitals caring for children undergoing surgery for CHD. <b>Results:</b> Responses from 45 respondent PC4 centers was analyzed; 71% of centers (n = 32) had a prophylactic anticoagulation protocol. Two of the 45 respondent centers utilized a protocol for proactive screening for CA-DVT; 64% of centers (29/45) treated CA-DVT for a duration of 6 to 12 weeks. Internal jugular central vein catheters (CVC) were the most common primary access in children who were 1 to 18 years of age undergoing surgery (89% [40/45] of centers) and in infants 1 to 12 months of age (73% [33/45] of centers). Significant variability CVC-type selection was reported in neonates (<30 days of age). More than half of centers reported avoiding upper extremity peripherally inserted central catheter placement in patients both prior to and after stage 2 palliation for single ventricle CHD (58% [26/45] and 53% [24/45], respectively). <b>Conclusions:</b> Significant variability in prevention and management of CA-DVT is reported among PC<sup>4</sup> centers. Only half of respondent PC4 centers reported having an established treatment protocol for CA-DVT. Consensus and evidence-based guidelines for the treatment of CA-DVT are not consistently followed with only 62% (28/45) of centers reported treating for the recommended 6 to 12 weeks with anticoagulation. There is high variability in CVC-type and location selection in neonates undergoing CHD surgery.

World Journal for Pediatric and Congenital Heart Surgery
Tufts University (US), Lurie Children's Hospital (US), Children's Hospital of Orange County (US), Children's Hospital of Philadelphia (US), Johns Hopkins University (US), Emory University (US), Medical College of Wisconsin (US), University of Michigan (US), University of California San Diego (US), Children's Hospital Colorado (US), Johns Hopkins All Children's Hospital (US), Maine Medical Center (US), Lurie Children's Hospital (US), Johns Hopkins Children's Center (US), Children's Healthcare of Atlanta (US), Texas Children's Hospital (US), C. S. Mott Children's Hospital (US), Barbara Bush Children’s Hospital (US), Robert H. Lurie Comprehensive Cancer Center of Northwestern University, University of Virginia (US), University of Pennsylvania (US), The University of Texas Southwestern Medical Center (US), University of Colorado Denver (US)
Openalex Percentile: Top 45%
Central Venous Catheters and Hemodialysis
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