Central Venous Catheter Selection, Management, and Treatment of Catheter-Associated Deep Vein Thrombosis in Children Undergoing Cardiac Surgery: A Survey of Pediatric Cardiac Critical Care Consortium Centers
<b>Objective:</b> Children undergoing surgery for congenital heart disease (CHD) are at risk for catheter-associated deep vein thrombosis (CA-DVT). We sought to understand the practice variations which may impact the risk for CA-DVT by conducting a comprehensive survey. <b>Methods:</b> Analysis of electronic survey of Pediatric Cardiac Critical Care Consortium (PC<sup>4</sup>) hospitals caring for children undergoing surgery for CHD. <b>Results:</b> Responses from 45 respondent PC4 centers was analyzed; 71% of centers (n = 32) had a prophylactic anticoagulation protocol. Two of the 45 respondent centers utilized a protocol for proactive screening for CA-DVT; 64% of centers (29/45) treated CA-DVT for a duration of 6 to 12 weeks. Internal jugular central vein catheters (CVC) were the most common primary access in children who were 1 to 18 years of age undergoing surgery (89% [40/45] of centers) and in infants 1 to 12 months of age (73% [33/45] of centers). Significant variability CVC-type selection was reported in neonates (<30 days of age). More than half of centers reported avoiding upper extremity peripherally inserted central catheter placement in patients both prior to and after stage 2 palliation for single ventricle CHD (58% [26/45] and 53% [24/45], respectively). <b>Conclusions:</b> Significant variability in prevention and management of CA-DVT is reported among PC<sup>4</sup> centers. Only half of respondent PC4 centers reported having an established treatment protocol for CA-DVT. Consensus and evidence-based guidelines for the treatment of CA-DVT are not consistently followed with only 62% (28/45) of centers reported treating for the recommended 6 to 12 weeks with anticoagulation. There is high variability in CVC-type and location selection in neonates undergoing CHD surgery.
Authors
- David K. Werho (ORCID: https://orcid.org/0000-0003-0048-9806)
- Brian S. Marcus (ORCID: https://orcid.org/0000-0001-5775-4143)
- Jason Patregnani (ORCID: https://orcid.org/0000-0002-7153-3352)
- Ashish A. Ankola
- Sirine Baltagi (ORCID: https://orcid.org/0009-0004-0928-2275)
- Laura A. Downey (ORCID: https://orcid.org/0000-0002-5334-3184)
- Wenying Zhang (ORCID: https://orcid.org/0000-0002-3513-1882)
- Kurt R. Schumacher (ORCID: https://orcid.org/0000-0001-8659-736X)
- Therese M. Giglia (ORCID: https://orcid.org/0000-0002-1571-6330)
- Jarrett Linder
- John S. Kim (ORCID: https://orcid.org/0000-0002-7403-222X)
- Darren Klugman (ORCID: https://orcid.org/0009-0008-4814-5723)
- Jessica Baylor
- Eric L. Bressler
- Justin Yeh
Institutions
- Tufts University (US)
- Lurie Children's Hospital (US)
- Children's Hospital of Orange County (US)
- Children's Hospital of Philadelphia (US)
- Johns Hopkins University (US)
- Emory University (US)
- Medical College of Wisconsin (US)
- University of Michigan (US)
- University of California San Diego (US)
- Children's Hospital Colorado (US)
- Johns Hopkins All Children's Hospital (US)
- Maine Medical Center (US)
- Lurie Children's Hospital (US)
- Johns Hopkins Children's Center (US)
- Children's Healthcare of Atlanta (US)
- Texas Children's Hospital (US)
- C. S. Mott Children's Hospital (US)
- Barbara Bush Children’s Hospital (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- University of Virginia (US)
- University of Pennsylvania (US)
- The University of Texas Southwestern Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- World Journal for Pediatric and Congenital Heart Surgery
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1177/21501351251391768
- Primary Topic
- Central Venous Catheters and Hemodialysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00