Machine Learning-Integrated Analysis of SULF1, CXCL8, and PBLD Expression as Discriminative Biomarkers for Early Detection and Prognosis in Colorectal Cancer
These four identified DEGs (SULF1, CXCL8, LRRC19, and PBLD) may contribute to the treatment of CRC as a new therapeutic target and provide valuable biomarkers for cancer metastasis research.The four identified DEGs were combined with machine learning to construct a CRC diagnostic model with high clinical application value.
Authors
- Fuxiang Zhou (ORCID: https://orcid.org/0000-0001-9216-5395)
- Li Zhang (ORCID: https://orcid.org/0009-0007-2824-6343)
- Yang Li (ORCID: https://orcid.org/0000-0002-7016-2246)
- Jianfeng Shi (ORCID: https://orcid.org/0000-0002-4945-034X)
- Hong Zhao (ORCID: https://orcid.org/0000-0001-8991-7824)
- Chao Mei (ORCID: https://orcid.org/0000-0002-3948-8897)
Institutions
- Fourth Affiliated Hospital of China Medical University (CN)
- Jinzhou Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- International Journal of General Medicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/ijgm.s553709
- Primary Topic
- Chemokine receptors and signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00