Cerebral blood flow in a tri-ethnic population: insights from pCASL perfusion MRI

Question Prevalence and distribution of arterial transit artefacts (ATAs) on arterial spin labelling MRI, and their relationship to sex, ethnicity, vascular anatomy, and cardiovascular parameters, have not been systematically investigated. Findings ATAs were most prevalent in African Caribbeans, particularly in MCA-PCA borderzones and PCA territories; no significant differences were found between White Europeans and South Asians. Clinical relevance Visual rating revealed substantial differences in the ATA distribution among ethnic populations, as well as between women and men. Recognising these specific patterns can help distinguish physiological from pathological perfusion, thereby enhancing diagnostic accuracy and treatment planning.

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Publication Details

Journal
European Radiology
Published
2025-12-03
DOI
https://doi.org/10.1007/s00330-025-12160-5
Citations
1
Primary Topic
Advanced MRI Techniques and Applications
Type
article
Field-Weighted Citation Impact
1.36

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article

Cerebral blood flow in a tri-ethnic population: insights from pCASL perfusion MRI

Magdalena Sokolska, Therese Tillin, David Atkinson, Carole H. Sudre et al.
1 citations
European Radiology
Advanced MRI Techniques and Applications
1.36
article

Cerebral blood flow in a tri-ethnic population: insights from pCASL perfusion MRI

Magdalena Sokolska, Therese Tillin, David Atkinson, Carole H. Sudre, Rafael Rehwald, Hans Rolf Jäger, Alun David Hughes, Nish Chaturvedi, Lorna Smith
article en
1 citations

Abstract

Question Prevalence and distribution of arterial transit artefacts (ATAs) on arterial spin labelling MRI, and their relationship to sex, ethnicity, vascular anatomy, and cardiovascular parameters, have not been systematically investigated. Findings ATAs were most prevalent in African Caribbeans, particularly in MCA-PCA borderzones and PCA territories; no significant differences were found between White Europeans and South Asians. Clinical relevance Visual rating revealed substantial differences in the ATA distribution among ethnic populations, as well as between women and men. Recognising these specific patterns can help distinguish physiological from pathological perfusion, thereby enhancing diagnostic accuracy and treatment planning.

European Radiology
University College London Hospitals NHS Foundation Trust (GB), Queen Mary University of London (GB), University of Cambridge (GB), Physiological Society (GB), King's College School (GB), UK Dementia Research Institute (GB), MRC Unit for Lifelong Health and Ageing (GB), National Hospital for Neurology and Neurosurgery (GB), University College London (GB)
Wellcome Trust, British Heart Foundation, Diabetes UK
Openalex Percentile: Top 14%
Advanced MRI Techniques and Applications
1.36
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Cerebral blood flow in a tri-ethnic population: insights from pCASL perfusion MRI — Magdalena Sokolska, Therese Tillin, et al. · European Radiology (2025) | TGRS Research Map | TGRS