Engineered extracellular vesicles for nose-to-brain co-delivery of chlorotoxin and curcumin for treatment of glioblastoma
The results suggest that CTX is not only an anti-tumor drug, but also a targeting ligand for enhanced cellular uptake. Therefore, enhanced therapeutic effects of CTX-EV/Cur may be due to synergistic effects of CTX and curcumin. Combined delivery of curcumin and CTX using CTX-EVs may be useful for treatment of glioblastoma.
Authors
- M. H. Son (ORCID: https://orcid.org/0000-0002-3651-2425)
- Jae Young Park (ORCID: https://orcid.org/0000-0002-6664-6846)
- Minhyung Lee (ORCID: https://orcid.org/0000-0002-7083-9296)
- Kangmin Park
Institutions
- Hanyang University (KR)
Publication Details
- Journal
- Nanomedicine
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1080/17435889.2025.2598338
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00