Influence of Multiple Risk Factor Management on the Onset and Progression of Chronic Kidney Disease in Patients With Hypertension
This study demonstrates a clear dose-response relationship between the number of controlled risk factors and the magnitude of kidney risk reduction. A comprehensive, multifactorial control strategy can progressively reduce and potentially normalize the excess kidney risk in hypertensive individuals. These findings support a more quantitative and stage-specific approach to hypertension management.
Authors
- Shuohua Chen (ORCID: https://orcid.org/0000-0002-6274-7471)
- Kuangyi Wu (ORCID: https://orcid.org/0009-0003-9482-216X)
- Qirui Song (ORCID: https://orcid.org/0009-0007-9340-4520)
- Maoxiang Zhao (ORCID: https://orcid.org/0000-0001-7027-5913)
- Michael Hecht Olsen (ORCID: https://orcid.org/0000-0003-2230-5780)
- Xiong Ding (ORCID: https://orcid.org/0000-0002-0947-3627)
- Zhe Huang (ORCID: https://orcid.org/0000-0001-6472-4743)
- Shouling Wu (ORCID: https://orcid.org/0000-0001-7095-6022)
- Xinyi Peng (ORCID: https://orcid.org/0000-0002-6003-2392)
- Yang Liu (ORCID: https://orcid.org/0000-0003-2678-5689)
- Jun Cai (ORCID: https://orcid.org/0000-0002-8928-9570)
Institutions
- University of Copenhagen (DK)
- Capital University (US)
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Peking Union Medical College Hospital (CN)
- Shantou University (CN)
- Wuhan University (CN)
- Kailuan General Hospital (CN)
- Beijing Anzhen Hospital (CN)
- Shantou University Medical College (CN)
- Second Affiliated Hospital of Shantou University Medical College (CN)
- Holbæk Sygehus (DK)
- Duke Kunshan University (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1161/jaha.125.041962
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00