Clinical utility and limitations of non‐invasive prenatal testing for chromosome 20 abnormalities: A retrospective study of 83 high‐risk pregnancies

NIPT demonstrates very limited accuracy for detecting chromosome 20 aneuploidies, while its performance in identifying CNVs is comparatively higher but remains modest. The favorable outcomes in most cases with normal diagnostic results underscore the importance of cautious reporting and interpretation of high-risk results for chromosome 20 abnormalities as well as comprehensive genetic counseling to guide pregnancy management.