TKI plus ICI versus ICI alone in high tumor burden hepatocellular carcinoma: a retrospective cohort study
Baseline CTP score, tumor burden, as well as AFP response during ICI treatment were the independent predictive factors for survival. Furthermore, among HCC patients beyond up-to-7 criteria, combination treatment was associated with improved survival than those without combination treatment.
Authors
- Po-Ting Lin (ORCID: https://orcid.org/0000-0001-9196-2376)
- Jenhui Chen (ORCID: https://orcid.org/0000-0002-8372-9221)
- Chen‐Chun Lin (ORCID: https://orcid.org/0000-0002-2907-2679)
- Wei Teng (ORCID: https://orcid.org/0000-0001-5663-1440)
- Chun‐Yen Lin (ORCID: https://orcid.org/0000-0003-3007-3190)
- Chung‐Wei Su (ORCID: https://orcid.org/0000-0003-2778-3618)
- Shi‐Ming Lin (ORCID: https://orcid.org/0000-0001-7527-6181)
- Yi‐Chung Hsieh
Institutions
- Chang Gung University (TW)
- Chang Gung Memorial Hospital (TW)
- Taipei Municipal YangMing Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- Taipei City Hospital (TW)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1007/s00432-025-06381-w
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chang Gung Medical Foundation